Molecular-genetic diagnostics of thrombophilic conditions - genetic bases of maternal, fetus and neonatal pathologies

Thrombophilia is one of the causes for development critical conditions. As approximately 90% the main causes of failure IVF is thrombophilia and polymorphisms of genes thrombophilia. Infertile couples and their children are liable to complications of venous and arterial thrombosis. Considering this fact it is required to generate special standard of examination basis on molecular-genetic diagnostics. To prevent vascular catastrophes it is necessary to identify molecular markers of inherited genes thrombophilia. We describe three case reports of clinically and molecular-genetic typing of thrombophilia.