ADVANTAGES OF SPECT/CT IN THE DIAGNOSIS OF PARATHYROID ADENOMA. CLINICAL CASE

Excessive secretion of parathyroid hormone produced by the parathyroid glands leads to hyperparathyroidism. The most common cause of primary hyperparathyroidism is parathyroid adenomas or their hyperplasia. To evaluate the diagnostic capabilities of the method of two-indicator scintigraphy of the parathyroid and the advantages of a hybrid study - single-photon emission computed tomography combined with X-ray computed tomography (SPECT/CT) for parathyroid adenoma located behind the left lobe of the thyroid in a patient with PGPT. A scintigraphic examination of the parathyroid was performed on the General Electric Discovery NM/CT 670 scanner after intravenous administration of radiopharmaceuticals Tc-99m-pertechnetate (NIFHI, Russia), and then Tc-99m- sestamibi (Diamed, Russia). The obtained data was processed on a computer using Xeleris 3 software. Based on the obtained results, it was concluded that the mass located anteriorly from the C6-7 vertebrae, actively accumulating Tc-99m-sestamibi, is a parathyroid adenoma. The accuracy of planar scintigraphy of parathyroid using Tc-99m-sestamibi varies from 74% to 95.2%. Hybrid method of SPECT/CT combines radionuclide diagnostics (SPECT) and X-ray diagnostics (CT), which makes it possible to determine more accurately the localization in cases with deep as well as ectopic location of parathyroid in the mediastinum, etc.