Socio-demographic processes of modern times are characterized by the steady aging of the population, which determines the increase in incidence of medical problems associated with late age. The result of applying epidemiological and statistical methods was the dynamic estimation of demographic indicators of the Sverdlovsk region and the epidemiological assessment of mental disorders later in the same area for the period 1995 to 2015 showed a significant increase in the incidence of mental disorders in the General population of the mentally ill.