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A study of patients with diabetes mellitus and diabetic microangiopathies showed that a comprehensive approach to the treatment of such patients, including the use of hydrochloric-chloride-sodium mineral water “Obukhovskaya” in combination with the course of “dry” carbonic baths in the sanatorium Obukhovsky, significantly improves the function the urinary system and the organ of vision, which is reflected in the improvement of kidney function and renal blood flow, as well as ophthalmological parameters.