The article presents the final scientific and scientific-methodological works of the Center for Social Work on the study of the main aspects of the effectiveness of the healthcare system of the Sverdlovsk region for 2020-2025. The main areas of research include: analysis of the state of mid-level medical personnel; study of the student contingent of the regional medical college; features of the medical volunteer movement. The materials of sociological research were used, including surveys, diagnostics and forecasting of situations. Particular attention was paid to issues of personnel risks and ways to increase the stability of employment, mentoring and layoff prevention. The research results are aimed at solving practical problems of increasing the efficiency of regional public health organizations and retaining qualified personnel.